N-alpha-Benzyloxycarbonyl-L-serine benzyl ester

N-alpha-Benzyloxycarbonyl-L-serine benzyl ester - Names and Identifiers

Name	Z-Ser-OBzl
Synonyms	Z-Ser-OBzl Z-L-Ser-OBzl CBZ-SER-OBZL benzyl L-serinate N-a-CBZ-L-Ser-O-Bzl Cbz-L-serinebenzylester N-Z-L-Serine benzyl ester benzyl N-[(benzyloxy)carbonyl]serinate BENZYLOXYCARBONYL-L-SERINE BENZYL ESTER N-(Benzyloxycarbonyl)serine benzyl ester benzyl N-[(benzyloxy)carbonyl]-L-serinate N-alpha-Benzyloxycarbonyl-L-serine benzyl ester (2S)-2-[(Benzyloxycarbonyl)amino]-3-hydroxypropionic acid benzyl ester (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-hydroxypropanoic acid benzyl ester
CAS	21209-51-8
InChI	InChI=1/C18H19NO5/c20-11-16(17(21)23-12-14-7-3-1-4-8-14)19-18(22)24-13-15-9-5-2-6-10-15/h1-10,16,20H,11-13H2,(H,19,22)/t16-/m0/s1

N-alpha-Benzyloxycarbonyl-L-serine benzyl ester - Physico-chemical Properties

Molecular Formula	C18H19NO5
Molar Mass	329.35
Density	1.253
Melting Point	83-86°C(lit.)
Boling Point	534.5±50.0 °C(Predicted)
Flash Point	277°C
Water Solubility	Slightly soluble in water.
Solubility	Chloroform, Methanol
Vapor Presure	2.97E-12mmHg at 25°C
Appearance	Solid
Color	White to Pale Yellow
pKa	10.46±0.46(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.58
MDL	MFCD00037824

N-alpha-Benzyloxycarbonyl-L-serine benzyl ester - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29242100

N-alpha-Benzyloxycarbonyl-L-serine benzyl ester - Introduction

Z-Ser-OBzl (Z-Ser-OBzl) is an organic compound whose chemical formula is C20H21NO5.

Nature:
Z-Ser-OBzl is a white crystalline solid, stable at room temperature. It is a water-insoluble compound, soluble in common organic solvents such as ethanol, acetone and dimethylformamide.

Use:
Z-Ser-OBzl are mainly used for Amine protecting groups in organic synthesis. It is usually used as a protecting group in peptide synthesis to prevent the amino group on the serine side chain from participating in the reaction and protect the reactivity of serine.

Method:
The preparation of the Z-Ser-OBzl can be carried out by the following steps: First, L-serine is reacted with benzyl alcohol to generate serine benzyl ester; Then, the generated serine benzyl ester is reacted with benzoyl chloride to generate Z-Ser-OBzl.

Safety Information:
Specific safety information about Z-Ser-OBzl and toxicity data are not widely reported. However, as an organic compound, when used, care should be taken to comply with general laboratory safety practices, such as wearing appropriate personal protective equipment, avoiding inhalation, skin contact and ingestion, and maintaining good ventilation conditions, and properly store and dispose of chemicals. For detailed safety and toxicity information, please refer to the relevant chemical substance safety data sheet.

Last Update：2024-04-10 22:29:15